Comparative antibacterial properties in vitro of seven olivanic acid derivatives: MM 4550, MM 13902, MM 17880, MM 22380, MM 22381, MM 22382 and MM 22383.
نویسندگان
چکیده
منابع مشابه
Four further antibiotics related to olivanic acid produced by Streptomyces olivaceus: fermentation, isolation, characterisation and biosynthetic studies.
Four beta-lactam antibiotics with beta-lactamase inhibitory activity MM 22380, MM 22381, MM 22382 and MM 22383 containing the carbapenem nucleus have been isolated from a culture of Streptomyces olivaceus ATCC 31365. Fermentation conditions for their production and methods for their isolation are described. Evidence for a biosynthetic link between these compounds and the previously described ol...
متن کاملmycin, N-acetylthienamycin and N-acetyldehydrothienamycin from S. cattleya7) and also a group of antibiotics, the epithienamycins A - D from S. flavogriseus.8,9) The olivanic acid derivatives
Streptomyces olivaceus ATCC 31365 produces a family of novel 1S-lactam antibiotics collectively referred to as the olivanic acids. Seven such compounds, MM 4550, MM 13902, MM 17880, MM 22380, MM 22381, MM 22382 and MM 22383 have been identified which have the same carbapenem nucleus but with different side chains attached to the nucleus. The compounds with an (8S) hydroxyethyl substituent and c...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1980
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.33.878